Anti-CCL21 antibody (71-120 aa) (STJ98793)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the Internal region of human CCL21 at the amino acid range 71-120
General Information
| Short Description | Rabbit polyclonal anti-C-C motif chemokine 21 (71-120 aa) for use in IHC, IF and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/IF/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | IHC-P 1:50-200ELISA 1:10000-20000IF 1:50-200 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CCL21 |
| Gene ID | 6366 |
| Uniprot ID | CCL21_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the Internal region of human CCL21 at the amino acid range 71-120 |
| Immunogen Region | 71-120 aa |
| Specificity | The antibody detects endogenous 6CKine |
Additional Info
| Function | Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Shows preferential activity towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4. |
| Protein Name | C-C Motif Chemokine 216ckineBeta-Chemokine Exodus-2Secondary Lymphoid-Tissue ChemokineSlcSmall-Inducible Cytokine A21 |
| Database Links | Reactome: R-HSA-380108Reactome: R-HSA-418594 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-C-C Motif Chemokine 21 antibodyAnti-6ckine antibodyAnti-Beta-Chemokine Exodus-2 antibodyAnti-Secondary Lymphoid-Tissue Chemokine antibodyAnti-Slc antibodyAnti-Small-Inducible Cytokine A21 antibodyAnti-CCL21 antibodyAnti-SCYA21 antibodyAnti-UNQ784 antibodyAnti-PRO1600 antibody |
Information sourced from Uniprot.org