Anti-CCDC65 antibody (STJA0009600)

SKU:
STJA0009600

Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Dynein regulatory complex subunit 2 is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:500-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CCDC65
Gene ID: 85478
Uniprot ID: DRC2_HUMAN
Specificity: This antibody detects endogenous levels of CCDC65 at Human, Mouse, Rat
Immunogen: Synthesized peptide derived from human CCDC65
Function Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Plays a critical role in the assembly of N-DRC and also stabilizes the assembly of multiple inner dynein arms and radial spokes. Coassembles with DRC1 to form a central scaffold needed for assembly of the N-DRC and its attachment to the outer doublet microtubules.
Protein Name Dynein Regulatory Complex Subunit 2
Coiled-Coil Domain-Containing Protein 65
Testis Development Protein Nyd-Sp28
Cellular Localisation Cytoplasm
Cytoskeleton
Flagellum Basal Body
Cell Projection
Cilium
Flagellum
Flagellum Axoneme
Alternative Antibody Names Anti-Dynein Regulatory Complex Subunit 2 antibody
Anti-Coiled-Coil Domain-Containing Protein 65 antibody
Anti-Testis Development Protein Nyd-Sp28 antibody
Anti-CCDC65 antibody
Anti-DRC2 antibody

Information sourced from Uniprot.org

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