| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal anti-Dynein regulatory complex subunit 2 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CCDC65 |
| Gene ID: | 85478 |
| Uniprot ID: | DRC2_HUMAN |
| Specificity: | This antibody detects endogenous levels of CCDC65 at Human, Mouse, Rat |
| Immunogen: | Synthesized peptide derived from human CCDC65 |
| Function | Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Plays a critical role in the assembly of N-DRC and also stabilizes the assembly of multiple inner dynein arms and radial spokes. Coassembles with DRC1 to form a central scaffold needed for assembly of the N-DRC and its attachment to the outer doublet microtubules. |
| Protein Name | Dynein Regulatory Complex Subunit 2Coiled-Coil Domain-Containing Protein 65Testis Development Protein Nyd-Sp28 |
| Database Links | |
| Cellular Localisation | CytoplasmCytoskeletonFlagellum Basal BodyCell ProjectionCiliumFlagellumFlagellum Axoneme |
| Alternative Antibody Names | Anti-Dynein Regulatory Complex Subunit 2 antibodyAnti-Coiled-Coil Domain-Containing Protein 65 antibodyAnti-Testis Development Protein Nyd-Sp28 antibodyAnti-CCDC65 antibodyAnti-DRC2 antibody |
Information sourced from Uniprot.org
