Anti-CCDC146 antibody (765-815 aa) (STJ193693)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human CC146 at the amino acid range 765-815
General Information
| Short Description | Rabbit polyclonal anti-Coiled-coil domain-containing protein 146 (765-815 aa) for use in WB in Human and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CCDC146 |
| Gene ID | 57639 |
| Uniprot ID | CC146_HUMAN |
| Immunogen | Synthesized peptide derived from the human CC146 at the amino acid range 765-815 |
| Immunogen Region | 765-815 aa |
| Specificity | This antibody detects endogenous levels of CC146 at Human/Rat |
Additional Info
| Function | Essential for sperm flagellum biogenesis and male fertility. |
| Protein Name | Coiled-Coil Domain-Containing Protein 146 |
| Database Links | |
| Cellular Localisation | CytoplasmCytoskeletonMicrotubule Organizing CenterCentrosomeCentrioleFlagellum AxonemeCilium Basal BodyMidbodyIn Sperm CellsWas Seen Localized To Only One Centriole Identified As The Mother Centriole By Co-Staining With Cep164In Other ExperimentsLocalization To Centrioles In Sperm Cells Was Not ObservedLocalizes To The Sperm Connecting Piece And Flagellum During Spermiogenesis And To The Flagellum In Spermatozoa From Cauda Of The EpididymisIn Sperm Cell FlagellumMay Be Associated With Tubulin Doublets(Microbial Infection) In Cells Infected With CTrachomatis IncmRecruited To The Periphery Of The Pathogen-Containing Vacuole But Recruitment Is Not Dependent On Incm |
| Alternative Antibody Names | Anti-Coiled-Coil Domain-Containing Protein 146 antibodyAnti-CCDC146 antibodyAnti-KIAA1505 antibody |
Information sourced from Uniprot.org