Anti-CCDC101 antibody [R08-9T-3] (STJA0033132)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1k
ImmunogenPeptide
General Information
| Short Description | Mouse monoclonal anti-CCDC101 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Mouse |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R08-9T-3 |
| Isotype | IgG1k |
| Conjugation | Unconjugated |
| Purification | Protein G |
| Dilution Range | WB 1:1000 |
| Formulation | Liquid in PBS, Glycerol and BSA |
| Storage Instruction | Store at-20°C. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | SGF29 |
| Gene ID | 112869 |
| Uniprot ID | SGF29_HUMAN |
| Immunogen | Peptide |
Additional Info
| Function | Chromatin reader component of some histone acetyltransferase (HAT) SAGA-type complexes like the TFTC-HAT, ATAC or STAGA complexes. SGF29 specifically recognizes and binds methylated 'Lys-4' of histone H3 (H3K4me), with a preference for trimethylated form (H3K4me3). In the SAGA-type complexes, SGF29 is required to recruit complexes to H3K4me. Involved in the response to endoplasmic reticulum (ER) stress by recruiting the SAGA complex to H3K4me, thereby promoting histone H3 acetylation and cell survival. Also binds non-histone proteins that are methylated on Lys residues: specifically recognizes and binds CGAS monomethylated on 'Lys-506'. |
| Protein Name | Saga-Associated Factor 29Coiled-Coil Domain-Containing Protein 101Saga Complex-Associated Factor 29 |
| Database Links | Reactome: R-HSA-3214847Reactome: R-HSA-9772755 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Saga-Associated Factor 29 antibodyAnti-Coiled-Coil Domain-Containing Protein 101 antibodyAnti-Saga Complex-Associated Factor 29 antibodyAnti-SGF29 antibodyAnti-CCDC101 antibody |
Information sourced from Uniprot.org