Anti-CBY1 antibody (71-121 aa) (STJ195041)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human CBY1 at the amino acid range 71-121
General Information
| Short Description | Rabbit polyclonal anti-Protein chibby homolog 1 (71-121 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CBY1 |
| Gene ID | 25776 |
| Uniprot ID | CBY1_HUMAN |
| Immunogen | Synthesized peptide derived from the human CBY1 at the amino acid range 71-121 |
| Immunogen Region | 71-121 aa |
| Specificity | This antibody detects endogenous levels of CBY1 at Human/Mouse/Rat |
Additional Info
| Function | Inhibits the Wnt/Wingless pathway by binding to CTNNB1/beta-catenin and inhibiting beta-catenin-mediated transcriptional activation through competition with TCF/LEF transcription factors. Has also been shown to play a role in regulating the intracellular trafficking of polycystin-2/PKD2 and possibly of other intracellular proteins. Promotes adipocyte and cardiomyocyte differentiation. |
| Protein Name | Protein Chibby Homolog 1Arpp-Binding ProteinCytosolic Leucine-Rich ProteinPigea-14Pkd2 Interactor - Golgi And Endoplasmic Reticulum-Associated 1 |
| Database Links | Reactome: R-HSA-3769402 |
| Cellular Localisation | Nucleus SpeckleCytoplasmCytoskeletonCilium Basal BodyMicrotubule Organizing CenterCentrosomeCentrioleGolgi ApparatusTrans-Golgi NetworkCell ProjectionCiliumFlagellumNucleus |
| Alternative Antibody Names | Anti-Protein Chibby Homolog 1 antibodyAnti-Arpp-Binding Protein antibodyAnti-Cytosolic Leucine-Rich Protein antibodyAnti-Pigea-14 antibodyAnti-Pkd2 Interactor - Golgi And Endoplasmic Reticulum-Associated 1 antibodyAnti-CBY1 antibodyAnti-ARB1 antibodyAnti-C22orf2 antibodyAnti-CBY antibodyAnti-PGEA1 antibodyAnti-HRIHFB2025 antibody |
Information sourced from Uniprot.org