| Host: | Rabbit |
| Applications: | WB |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Protein chibby homolog 1 (71-121 aa) is suitable for use in Western Blot research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-2000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CBY1 |
| Gene ID: | 25776 |
| Uniprot ID: | CBY1_HUMAN |
| Immunogen Region: | 71-121 aa |
| Specificity: | This antibody detects endogenous levels of CBY1 at Human/Mouse/Rat |
| Immunogen: | Synthesized peptide derived from the human CBY1 at the amino acid range 71-121 |
| Function | Inhibits the Wnt/Wingless pathway by binding to CTNNB1/beta-catenin and inhibiting beta-catenin-mediated transcriptional activation through competition with TCF/LEF transcription factors. Has also been shown to play a role in regulating the intracellular trafficking of polycystin-2/PKD2 and possibly of other intracellular proteins. Promotes adipocyte and cardiomyocyte differentiation. |
| Protein Name | Protein Chibby Homolog 1 Arpp-Binding Protein Cytosolic Leucine-Rich Protein Pigea-14 Pkd2 Interactor - Golgi And Endoplasmic Reticulum-Associated 1 |
| Database Links | Reactome: R-HSA-3769402 |
| Cellular Localisation | Nucleus Speckle Cytoplasm Cytoskeleton Cilium Basal Body Microtubule Organizing Center Centrosome Centriole Golgi Apparatus Trans-Golgi Network |
| Alternative Antibody Names | Anti-Protein Chibby Homolog 1 antibody Anti-Arpp-Binding Protein antibody Anti-Cytosolic Leucine-Rich Protein antibody Anti-Pigea-14 antibody Anti-Pkd2 Interactor - Golgi And Endoplasmic Reticulum-Associated 1 antibody Anti-CBY1 antibody Anti-ARB1 antibody Anti-C22orf2 antibody Anti-CBY antibody Anti-PGEA1 antibody Anti-HRIHFB2025 antibody |
Information sourced from Uniprot.org