| Short Description : | Mouse monoclonal anti-Chromobox protein homolog 1 for use in WB in Human, Mouse, Rat, Cow, Chicken, Dog and Pig samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB |
| Host: | Mouse |
| Reactivity: | Human/Mouse/Rat/Cow/Chicken/Dog/Pig |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Monoclonal |
| Conjugation: | Unconjugated |
| Concentration: | 1 mg/mL |
| Purification: | Affinity purification |
| Dilution Range: | WB 1:1000-1:2000 |
| Formulation: | Liquid in 0.1M Tris-Glycine (pH7.4, 150 mM NaCl) , 0.2% Sodium Azide and 50% Glycerol. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CBX1 |
| Gene ID: | 10951 |
| Uniprot ID: | CBX1_HUMAN |
| Immunogen: | Purified recombinant human HP1 Beta protein fragments expressed in E.coli. |
| Specificity: | HP1 Beta Monoclonal Antibody detects endogenous levels of HP1 Beta protein. |
| Post Translational Modifications | Not phosphorylated. Ubiquitinated. |
| Function | Component of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane. |
| Protein Name | Chromobox Protein Homolog 1Hp1hsbetaHeterochromatin Protein 1 Homolog BetaHp1 BetaHeterochromatin Protein P25M31Modifier 1 ProteinP25beta |
| Database Links | Reactome: R-HSA-9609690 |
| Cellular Localisation | NucleusUnassociated With Chromosomes During Mitosis |
| Alternative Antibody Names | Anti-Chromobox Protein Homolog 1 antibodyAnti-Hp1hsbeta antibodyAnti-Heterochromatin Protein 1 Homolog Beta antibodyAnti-Hp1 Beta antibodyAnti-Heterochromatin Protein P25 antibodyAnti-M31 antibodyAnti-Modifier 1 Protein antibodyAnti-P25beta antibodyAnti-CBX1 antibodyAnti-CBX antibody |
Information sourced from Uniprot.org
