Anti-CBX1 antibody (50-100 aa) (STJ13100976)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from aa region 50-100 of human CBX1 conjugated to an immunogenic carrier protein was used as the antigen.
General Information
| Short Description | Rabbit polyclonal anti-CBX1 (50-100 aa) for use in IHC and WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB (confirmed by recombinant protein). A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20Β°C for long term storage and refrigerated at 2-8Β°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | CBX1 |
| Gene ID | 10951 |
| Uniprot ID | CBX1_HUMAN |
| Immunogen | A synthetic peptide from aa region 50-100 of human CBX1 conjugated to an immunogenic carrier protein was used as the antigen. |
| Immunogen Region | 50-100 aa |
| Specificity | Specific for CBX1. |
Additional Info
| Post Translational Modifications | Not phosphorylated. Ubiquitinated. |
| Function | Component of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane. |
| Protein Name | Chromobox Protein Homolog 1Hp1hsbetaHeterochromatin Protein 1 Homolog BetaHp1 BetaHeterochromatin Protein P25M31Modifier 1 ProteinP25beta |
| Database Links | Reactome: R-HSA-9609690 |
| Cellular Localisation | NucleusUnassociated With Chromosomes During Mitosis |
| Alternative Antibody Names | Anti-Chromobox Protein Homolog 1 antibodyAnti-Hp1hsbeta antibodyAnti-Heterochromatin Protein 1 Homolog Beta antibodyAnti-Hp1 Beta antibodyAnti-Heterochromatin Protein P25 antibodyAnti-M31 antibodyAnti-Modifier 1 Protein antibodyAnti-P25beta antibodyAnti-CBX1 antibodyAnti-CBX antibody |
Information sourced from Uniprot.org