Anti-ZNG1A antibody (61-111 aa) (STJ196003)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human CBWD1 at the amino acid range 61-111
General Information
| Short Description | Rabbit polyclonal anti-Zinc-regulated GTPase metalloprotein activator 1A (61-111 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ZNG1A |
| Gene ID | 55871 |
| Uniprot ID | ZNG1A_HUMAN |
| Immunogen | Synthesized peptide derived from the human CBWD1 at the amino acid range 61-111 |
| Immunogen Region | 61-111 aa |
| Specificity | This antibody detects endogenous levels of CBWD1 at Human/Mouse/Rat |
Additional Info
| Function | Zinc chaperone that directly transfers zinc cofactor to target metalloproteins, thereby activating them. Catalyzes zinc insertion into the active site of methionine aminopeptidase METAP1, which function to cleave the initiator methionine from polypeptides during or after protein translation. Mechanistically, the N-terminal psi-PxLVp motif binds to the C6H2-type zinc finger of inactive form of METAP1. After formation of the docked complex, zinc is transferred from the CXCC motif in the GTPase domain of ZNG1A to the zinc binding site in the peptidase domain of METAP1 in a process requiring GTP hydrolysis. GTP/GDP exchange is required for release of active METAP1. |
| Protein Name | Zinc-Regulated Gtpase Metalloprotein Activator 1aCobalamin Synthase W Domain-Containing Protein 1Cobw Domain-Containing Protein 1Npc-A-6 Cobw Domain-Containing Protein 1Npc-A-6 |
| Database Links | |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Zinc-Regulated Gtpase Metalloprotein Activator 1a antibodyAnti-Cobalamin Synthase W Domain-Containing Protein 1 antibodyAnti-Cobw Domain-Containing Protein 1 antibodyAnti-Npc-A-6 Cobw Domain-Containing Protein 1 antibodyAnti-Npc-A-6 antibodyAnti-ZNG1A antibodyAnti-CBWD1 antibody |
Information sourced from Uniprot.org