| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Zinc-regulated GTPase metalloprotein activator 1A (61-111 aa) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
ZNG1A |
| Gene ID: |
55871 |
| Uniprot ID: |
ZNG1A_HUMAN |
| Immunogen Region: |
61-111 aa |
| Specificity: |
This antibody detects endogenous levels of CBWD1 at Human/Mouse/Rat |
| Immunogen: |
Synthesized peptide derived from the human CBWD1 at the amino acid range 61-111 |
| Function | Zinc chaperone that directly transfers zinc cofactor to target metalloproteins, thereby activating them. Catalyzes zinc insertion into the active site of methionine aminopeptidase METAP1, which function to cleave the initiator methionine from polypeptides during or after protein translation. Mechanistically, the N-terminal psi-PxLVp motif binds to the C6H2-type zinc finger of inactive form of METAP1. After formation of the docked complex, zinc is transferred from the CXCC motif in the GTPase domain of ZNG1A to the zinc binding site in the peptidase domain of METAP1 in a process requiring GTP hydrolysis. GTP/GDP exchange is required for release of active METAP1. |
| Protein Name | Zinc-Regulated Gtpase Metalloprotein Activator 1aCobalamin Synthase W Domain-Containing Protein 1Cobw Domain-Containing Protein 1Npc-A-6 Cobw Domain-Containing Protein 1Npc-A-6 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Zinc-Regulated Gtpase Metalloprotein Activator 1a antibodyAnti-Cobalamin Synthase W Domain-Containing Protein 1 antibodyAnti-Cobw Domain-Containing Protein 1 antibodyAnti-Npc-A-6 Cobw Domain-Containing Protein 1 antibodyAnti-Npc-A-6 antibodyAnti-ZNG1A antibodyAnti-CBWD1 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
