Anti-CBR3 antibody [R06-7B3] (STJA0034123)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide of human CBR3
General Information
| Short Description | Rabbit monoclonal anti-CBR3 for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R06-7B3 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000 |
| Formulation | 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | CBR3 |
| Gene ID | 874 |
| Uniprot ID | CBR3_HUMAN |
| Immunogen | A synthetic peptide of human CBR3 |
Additional Info
| Tissue Specificity | Detected in ovary, pancreas, intestine, colon, kidney, brain, thymus, lung, heart, liver, spleen, leukocyte, prostate and testis. |
| Function | Catalyzes the NADPH-dependent reduction of carbonyl compounds to their corresponding alcohols. Has low NADPH-dependent oxidoreductase activity. Acts on several orthoquinones, acts as well on non-quinone compounds, such as isatin or on the anticancer drug oracin. Best substrates for CBR3 is 1,2- naphthoquinone, hence could play a role in protection against cytotoxicity of exogenous quinones. Exerts activity toward ortho-quinones but not paraquinones. No endogenous substrate for CBR3 except isatin has been identified. |
| Protein Name | Carbonyl Reductase Nadph 3Nadph-Dependent Carbonyl Reductase 3Quinone Reductase Cbr3Short Chain Dehydrogenase/Reductase Family 21c Member 2 |
| Database Links | Reactome: R-HSA-211945 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Carbonyl Reductase Nadph 3 antibodyAnti-Nadph-Dependent Carbonyl Reductase 3 antibodyAnti-Quinone Reductase Cbr3 antibodyAnti-Short Chain Dehydrogenase/Reductase Family 21c Member 2 antibodyAnti-CBR3 antibodyAnti-SDR21C2 antibody |
Information sourced from Uniprot.org