| Host: |
Rabbit |
| Applications: |
WB/IHC |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Caveolae-Associated Protein 2 (325-425) is suitable for use in Western Blot and Immunohistochemistry research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.05% Proclin300, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:1000IHC-P 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CAVIN2 |
| Gene ID: |
8436 |
| Uniprot ID: |
CAVN2_HUMAN |
| Immunogen Region: |
325-425 |
| Immunogen: |
A synthetic peptide corresponding to a sequence within amino acids 325-425 of human CAVIN2 (NP_004648.1). |
| Immunogen Sequence: |
PNDQEEESFAEGHSEASLAS ALVEGEIAEEAAEKATSRGS NSGMDSNIDLTIVEDEEEES VALEQAQKVRYEGSYALTSE EAERSDGDPVQPAVLQVHQT S |
| Tissue Specificity | Highly expressed in heart and lung, and expressed at lower levels in brain, kidney, liver, pancreas, placenta, and skeletal muscle. |
| Post Translational Modifications | Phosphorylated on Ser residues. |
| Function | Plays an important role in caveolar biogenesis and morphology. Regulates caveolae morphology by inducing membrane curvature within caveolae. Plays a role in caveola formation in a tissue-specific manner. Required for the formation of caveolae in the lung and fat endothelia but not in the heart endothelia. Negatively regulates the size or stability of CAVIN complexes in the lung endothelial cells. May play a role in targeting PRKCA to caveolae. |
| Protein Name | Caveolae-Associated Protein 2Cavin-2Ps-P68Phosphatidylserine-Binding ProteinSerum Deprivation-Response Protein |
| Cellular Localisation | CytoplasmCytosolMembraneCaveolaLocalizes In The Caveolae In A Caveolin-Dependent Manner |
| Alternative Antibody Names | Anti-Caveolae-Associated Protein 2 antibodyAnti-Cavin-2 antibodyAnti-Ps-P68 antibodyAnti-Phosphatidylserine-Binding Protein antibodyAnti-Serum Deprivation-Response Protein antibodyAnti-CAVIN2 antibodyAnti-SDPR antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
