Anti-CAT antibody (1-225) (STJ113364)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal CAT (1-225) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CAT |
| Gene ID | 847 |
| Uniprot ID | CATA_HUMAN |
| Immunogen Region | 1-225 |
| Immunogen Sequence | MADSRDPASDQMQHWKEQRA AQKADVLTTGAGNPVGDKLN VITVGPRGPLLVQDVVFTDE MAHFDRERIPERVVHAKGAG AFGYFEVTHDITKYSKAKVF EHIGKKTPIAVRFSTVAGES GSADTVRDPRGFAVKFYTED GNWDLVGNNTPIFFIRDPIL FPSFIHSQKRNPQTHLKDPD MVWDFWSLRPESLHQVSFLF SDRGIPDGHRHMNGYGSHTF KLVNA |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-225 of human Catalasealase (NP_001743.1). |
Additional Info
| Function | Catalyzes the degradation of hydrogen peroxide (H(2)O(2)) generated by peroxisomal oxidases to water and oxygen, thereby protecting cells from the toxic effects of hydrogen peroxide. Promotes growth of cells including T-cells, B-cells, myeloid leukemia cells, melanoma cells, mastocytoma cells and normal and transformed fibroblast cells. |
| Protein Name | Catalase |
| Database Links | Reactome: R-HSA-3299685Reactome: R-HSA-6798695Reactome: R-HSA-9033241Reactome: R-HSA-9615017Reactome: R-HSA-9841251 |
| Cellular Localisation | Peroxisome Matrix |
| Alternative Antibody Names | Anti-Catalase antibodyAnti-CAT antibody |
Information sourced from Uniprot.org