Anti-CAST antibody (STJA0037844)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human Calpastatin
General Information
| Short Description | Rabbit monoclonal anti-CAST for use in IHC-P in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-P |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Purified |
| Dilution Range | IHC 1:100-1:200 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | CAST |
| Gene ID | 831 |
| Uniprot ID | ICAL_HUMAN |
| Immunogen | A synthesized peptide derived from human Calpastatin |
Additional Info
| Post Translational Modifications | The N-terminus is blocked. |
| Function | Specific inhibition of calpain (calcium-dependent cysteine protease). Plays a key role in postmortem tenderization of meat and have been proposed to be involved in muscle protein degradation in living tissue. |
| Protein Name | CalpastatinCalpain InhibitorSperm Bs-17 Component |
| Database Links | Reactome: R-HSA-1474228Reactome: R-HSA-8862803 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Calpastatin antibodyAnti-Calpain Inhibitor antibodyAnti-Sperm Bs-17 Component antibodyAnti-CAST antibody |
Information sourced from Uniprot.org