Anti-Caspr1 antibody [R04-3E1] (STJA0036521)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human Caspr
General Information
| Short Description | Rabbit monoclonal anti-Caspr1 for use in WB and IHC-P in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R04-3E1 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Chromatography |
| Dilution Range | WB 1:500-1:1000IHC 1:50-1:100 |
| Formulation | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | CNTNAP1 |
| Gene ID | 8506 |
| Uniprot ID | CNTP1_HUMAN |
| Immunogen | A synthesized peptide derived from human Caspr |
Additional Info
| Tissue Specificity | Predominantly expressed in brain. Weak expression detected in ovary, pancreas, colon, lung, heart, intestine and testis. |
| Function | Required, with CNTNAP2, for radial and longitudinal organization of myelinated axons. Plays a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Demarcates the paranodal region of the axo-glial junction. In association with contactin involved in the signaling between axons and myelinating glial cells. |
| Protein Name | Contactin-Associated Protein 1CasprCaspr1Neurexin IvNeurexin-4P190 |
| Database Links | Reactome: R-HSA-447043 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinCell JunctionParanodal Septate Junction |
| Alternative Antibody Names | Anti-Contactin-Associated Protein 1 antibodyAnti-Caspr antibodyAnti-Caspr1 antibodyAnti-Neurexin Iv antibodyAnti-Neurexin-4 antibodyAnti-P190 antibodyAnti-CNTNAP1 antibodyAnti-CASPR antibodyAnti-NRXN4 antibody |
Information sourced from Uniprot.org