| Tissue Specificity | Predominantly expressed in brain. Weak expression detected in ovary, pancreas, colon, lung, heart, intestine and testis. |
| Function | Required, with CNTNAP2, for radial and longitudinal organization of myelinated axons. Plays a role in the formation of functional distinct domains critical for saltatory conduction of nerve impulses in myelinated nerve fibers. Demarcates the paranodal region of the axo-glial junction. In association with contactin involved in the signaling between axons and myelinating glial cells. |
| Protein Name | Contactin-Associated Protein 1CasprCaspr1Neurexin IvNeurexin-4P190 |
| Database Links | Reactome: R-HSA-447043 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinCell JunctionParanodal Septate Junction |
| Alternative Antibody Names | Anti-Contactin-Associated Protein 1 antibodyAnti-Caspr antibodyAnti-Caspr1 antibodyAnti-Neurexin Iv antibodyAnti-Neurexin-4 antibodyAnti-P190 antibodyAnti-CNTNAP1 antibodyAnti-CASPR antibodyAnti-NRXN4 antibody |
Information sourced from Uniprot.org
