Anti-Caspase-12 antibody [SRM14576] (STJ11109306)

SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthetic peptide. This information is considered to be commercially sensitive.
STJ11109306
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General Information

Short DescriptionRabbit monoclonal Caspase-12 antibody for use in WB, IF-P, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/IF-P/IHC-P/ELISA
HostRabbit
ReactivityHuman/Mouse/Rat
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityMonoclonal
Clone IDSRM14576
IsotypeIgG
ConjugationUnconjugated
PurificationAffinity purification
Dilution RangeWB, 1:1000-1:2000
IF-P, 1:200-1:800
IHC-P, 1:500-1:2000
ELISA, Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Storage InstructionStore at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolCASP12
Gene ID100506742
Uniprot IDCASPC_HUMAN
ImmunogenSynthetic peptide. This information is considered to be commercially sensitive.

Additional Info

Tissue Specificity Widely expressed, with highest levels in lung.
Function May function as a negative regulator of inflammatory responses and innate immunity. May reduce cytokine release in response to bacterial lipopolysaccharide during infection. Reduces activation of NF-kappa-B in response to TNF. May lack protease activity (Probable).
Protein Name Inactive Caspase-12
Casp-12
Database Links
Cellular Localisation
Alternative Antibody Names Anti-Inactive Caspase-12 antibody
Anti-Casp-12 antibody
Anti-CASP12 antibody
Anti-UNQ9415 antibody
Anti-PRO34398 antibody

Information sourced from Uniprot.org

Citations

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