![Anti-Cardiotin antibody [SR-2] (STJ16100265)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/148983/346619/STJ16100265_1__23483.1681998686.png?c=1 "Anti-Cardiotin antibody [SR-2] (STJ16100265)")
![Anti-Cardiotin antibody [SR-2] (STJ16100265)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/124x110/products/148983/346620/STJ16100265_2__38436.1681998686.png?c=1 "Anti-Cardiotin antibody [SR-2] (STJ16100265)")
![Anti-Cardiotin antibody [SR-2] (STJ16100265)](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/1280x1280/products/148983/346619/STJ16100265_1__23483.1681998686.png?c=1 "Anti-Cardiotin antibody [SR-2] (STJ16100265)")
Anti-Cardiotin antibody [SR-2] (STJ16100265)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgM
Immunogen100 kDa cardiotin subunit
General Information
| Short Description | Mouse monoclonal anti-Cardiotin for use in IHC-F, IHC-P and WB in Human and Swine samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC-F/IHC-P/WB |
| Host | Mouse |
| Reactivity | Human/Swine |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SR-2 |
| Isotype | IgM |
| Conjugation | Unconjugated |
| Dilution Range | IHC-F 1:25-1:100IHC-P 1:25-1:100WB 1:50-1:500 |
| Formulation | PBS with 0.09% sodium azide |
| Storage Instruction | Store at 2-8°C for up to 1-year, upon receipt. |
Target Information
| Immunogen | 100 kDa cardiotin subunit |
Additional Info
| Background | Cardiotin is a high molecular weight protein complex (300 kDa) located in the mitochondria of cardiomyocytes and skeletal muscle. The cardiotin structure exists of subunits of 60 kDa and 100 kDa, probably in a tetrameric configuRation. Both subunits contain the same amino-terminal 14 amino-acid sequence, showing high homology to Human skeletal muscle Alpha-actinin. During cardiac contractile dysfunction and myocard cell differentiation, the cardiotin distribution is affected. Compared to other structural proteins, cardiotin is one of the first to respond to insults (ischemia, fibrillation) that influence the functional status of cardiomyocytes. SR-2 reacts with cardiomyocytes, skeletal muscle, stromal and epithelial cells as well in vivo as in vitro. |
Information sourced from Uniprot.org