Anti-CARD19 antibody (1-100) (STJ115162)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
STJ115162
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General Information

Short DescriptionRabbit polyclonal CARD19 (1-100) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/ELISA
HostRabbit
ReactivityHuman/Mouse
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
ConcentrationLot specific
PurificationAffinity purification
Dilution RangeWB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
FormulationPBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Storage InstructionStore at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolCARD19
Gene ID84270
Uniprot IDCAR19_HUMAN
Immunogen Region1-100
Immunogen SequenceMTDQTYCDRLVQDTPFLTGH GRLSEQQVDRIILQLNRYYP QILTNKEAEKFRNPKASLRV RLCDLLSHLQRSGERDCQEF YRALYIHAQPLHSRLPSRHA
SpecificityRecombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human CARD19 (NP_115686.3).

Additional Info

Tissue Specificity Expressed in ovary, testis, placenta, skeletal muscle, kidney, lung, heart and liver (at protein level). Expressed in thymus and brain.
Function Plays a role in inhibiting the effects of BCL10-induced activation of NF-kappa-B. May inhibit the phosphorylation of BCL10 in a CARD-dependent manner.
Protein Name Caspase Recruitment Domain-Containing Protein 19
Bcl10-Interacting Card Protein
Bincard
Database Links
Cellular Localisation Isoform 1: Nucleus
Coexpression With Bcl10 Induced Translocation From Nucleus To Cytosol
Isoform 2: Endoplasmic Reticulum Membrane
Single-Pass Membrane Protein
Mitochondrion Membrane
Alternative Antibody Names Anti-Caspase Recruitment Domain-Containing Protein 19 antibody
Anti-Bcl10-Interacting Card Protein antibody
Anti-Bincard antibody
Anti-CARD19 antibody
Anti-C9orf89 antibody

Information sourced from Uniprot.org

Citations

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