Anti-CARD17P antibody (22-72 aa) (STJ198168)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human CAR17 at the amino acid range 22-72
General Information
| Short Description | Rabbit polyclonal anti-Putative caspase recruitment domain-containing protein 17P (22-72 aa) for use in WB in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:1000-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CARD17PUniprot ID=CAR17_HUMAN" |
| Immunogen | Synthesized peptide derived from the human CAR17 at the amino acid range 22-72 |
| Immunogen Region | 22-72 aa |
| Specificity | This antibody detects endogenous levels of human CAR17 |
Additional Info
| Function | Regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-IL-1beta/IL1B and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. However, unlike CASP1, do not induce NF-kappa-B activation. |
| Protein Name | Putative Caspase Recruitment Domain-Containing Protein 17pCaspase-1 Inhibitor IncaInhibitory Caspase Recruitment Domain Protein |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Putative Caspase Recruitment Domain-Containing Protein 17p antibodyAnti-Caspase-1 Inhibitor Inca antibodyAnti-Inhibitory Caspase Recruitment Domain Protein antibodyAnti-CARD17P antibodyAnti-CARD17 antibodyAnti-INCA antibody |
Information sourced from Uniprot.org