| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:1000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | CARD10 |
| Gene ID: | 29775 |
| Uniprot ID: | CAR10_HUMAN |
| Immunogen Region: | 863-1032 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 863-1032 of human CARD10 (NP_055365.2). |
| Immunogen Sequence: | LLDLPSSRLDFQVCPAESLS GEELCPSSAPGAPKAQPATP GLGSRIRAIQESVGKKHCLL ELGARGVRELVQNEIYPIVI HVEVTEKNVREVRGLLGRPG WRDSELLRQCRGSEQVLWGL PCSWVQVPAHEWGHAEELAK VVRGRILQEQARLVWVECGS SRGCPSSSEA |
| Tissue Specificity | Detected in adult heart, kidney and liver.lower levels in intestine, placenta, muscle and lung. Also found in fetal lung, liver and kidney. |
| Function | Scaffold protein that plays an important role in mediating the activation of NF-kappa-B via BCL10 or EGFR. |
| Protein Name | Caspase Recruitment Domain-Containing Protein 10Card-Containing Maguk Protein 3Carma 3 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Caspase Recruitment Domain-Containing Protein 10 antibodyAnti-Card-Containing Maguk Protein 3 antibodyAnti-Carma 3 antibodyAnti-CARD10 antibodyAnti-CARMA3 antibody |
Information sourced from Uniprot.org