Anti-CAPZA2 antibody (1-286) (STJ22888)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal CAPZA2 (1-286) antibody for use in WB, IHC-P and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.09% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CAPZA2 |
| Gene ID | 830 |
| Uniprot ID | CAZA2_HUMAN |
| Immunogen Region | 1-286 |
| Immunogen Sequence | MADLEEQLSDEEKVRIAAKF IIHAPPGEFNEVFNDVRLLL NNDNLLREGAAHAFAQYNLD QFTPVKIEGYEDQVLITEHG DLGNGKFLDPKNRICFKFDH LRKEATDPRPCEVENAVESW RTSVETALRAYVKEHYPNGV CTVYGKKIDGQQTIIACIES HQFQAKNFWNGRWRSEWKFT ITPSTTQVVGILKIQVHYYE DGNVQLVSHKDIQDSLTVSN EVQTAKEFIKIVEAAENEY |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-286 of human CAPZA2 (NP_006127.1). |
Additional Info
| Function | F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. |
| Protein Name | F-Actin-Capping Protein Subunit Alpha-2Capz Alpha-2 |
| Database Links | Reactome: R-HSA-2132295Reactome: R-HSA-3371497Reactome: R-HSA-6807878Reactome: R-HSA-6811436Reactome: R-HSA-879415Reactome: R-HSA-9662360Reactome: R-HSA-983231 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-F-Actin-Capping Protein Subunit Alpha-2 antibodyAnti-Capz Alpha-2 antibodyAnti-CAPZA2 antibody |
Information sourced from Uniprot.org