| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CAPRIN2 (88-329) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CAPRIN2 |
| Gene ID: |
65981 |
| Uniprot ID: |
CAPR2_HUMAN |
| Immunogen Region: |
88-329 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 88-329 of CAPRIN2 (NP_001002259.1). |
| Immunogen Sequence: |
QVNHSQHGESQRALSPLQST LSSAASPSQAYETYIENGLI CLKHKIRNIEKKKLKLEDYK DRLKSGEHLNPDQLEAVEKY EEVLHNLEFAKELQKTFSGL SLDLLKAQKKAQRREHMLKL EAEKKKLRTILQVQYVLQNL TQEHVQKDFKGGLNGAVYLP SKELDYLIKFSKLTCPERNE SLSVEDQMEQSSLYFWDLLE GSEKAVVGTTYKHLKDLLSK LLNSGYFESIPVPKNAKEK |
| Tissue Specificity | Detected in all tissues tested with highest levels of expression in brain and spleen. |
| Function | Promotes phosphorylation of the Wnt coreceptor LRP6, leading to increased activity of the canonical Wnt signaling pathway. Facilitates constitutive LRP6 phosphorylation by CDK14/CCNY during G2/M stage of the cell cycle, which may potentiate cells for Wnt signaling. May regulate the transport and translation of mRNAs, modulating for instance the expression of proteins involved in synaptic plasticity in neurons. Involved in regulation of growth as erythroblasts shift from a highly proliferative state towards their terminal phase of differentiation. May be involved in apoptosis. |
| Protein Name | Caprin-2C1q Domain-Containing Protein 1Cytoplasmic Activation/Proliferation-Associated Protein 2Gastric Cancer Multidrug Resistance-Associated ProteinProtein Eeg-1Rna Granule Protein 140 |
| Cellular Localisation | Isoform 1: CytoplasmIsoform 2: MitochondrionCytoplasmExpressed Throughout The CytoplasmIsoform 5: MitochondrionColocalizes With Aggregated MitochondriaCell MembranePeripheral Membrane Protein |
| Alternative Antibody Names | Anti-Caprin-2 antibodyAnti-C1q Domain-Containing Protein 1 antibodyAnti-Cytoplasmic Activation/Proliferation-Associated Protein 2 antibodyAnti-Gastric Cancer Multidrug Resistance-Associated Protein antibodyAnti-Protein Eeg-1 antibodyAnti-Rna Granule Protein 140 antibodyAnti-CAPRIN2 antibodyAnti-C1QDC1 antibodyAnti-EEG1 antibodyAnti-KIAA1873 antibodyAnti-RNG140 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
