Anti-CAPON antibody (STJA0037471)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenPeptide
General Information
| Short Description | Rabbit monoclonal anti-CAPON for use in WB, ICC, IF and FC in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ICC/IF/FC |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Purified |
| Dilution Range | WB-1:1000-1:5000ICC/IF-1:20-1:50FC-1:50-1:100 |
| Formulation | Liquid in 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | NOS1AP |
| Gene ID | 9722 |
| Uniprot ID | CAPON_HUMAN |
| Immunogen | Peptide |
Additional Info
| Tissue Specificity | Expressed in kidney glomeruli podocytes. |
| Function | Adapter protein involved in neuronal nitric-oxide (NO) synthesis regulation via its association with nNOS/NOS1. The complex formed with NOS1 and synapsins is necessary for specific NO and synapsin functions at a presynaptic level. Mediates an indirect interaction between NOS1 and RASD1 leading to enhance the ability of NOS1 to activate RASD1. Competes with DLG4 for interaction with NOS1, possibly affecting NOS1 activity by regulating the interaction between NOS1 and DLG4. In kidney podocytes, plays a role in podosomes and filopodia formation through CDC42 activation. |
| Protein Name | Carboxyl-Terminal Pdz Ligand Of Neuronal Nitric Oxide Synthase ProteinC-Terminal Pdz Ligand Of Neuronal Nitric Oxide Synthase ProteinNitric Oxide Synthase 1 Adaptor Protein |
| Database Links | |
| Cellular Localisation | Cell ProjectionFilopodiumPodosome |
| Alternative Antibody Names | Anti-Carboxyl-Terminal Pdz Ligand Of Neuronal Nitric Oxide Synthase Protein antibodyAnti-C-Terminal Pdz Ligand Of Neuronal Nitric Oxide Synthase Protein antibodyAnti-Nitric Oxide Synthase 1 Adaptor Protein antibodyAnti-NOS1AP antibodyAnti-CAPON antibodyAnti-KIAA0464 antibody |
Information sourced from Uniprot.org