Anti-CAPN6 antibody (STJ190643)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from part of the human protein
General Information
| Short Description | Rabbit polyclonal anti-Calpain-6 for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CAPN6 |
| Gene ID | 827 |
| Uniprot ID | CAN6_HUMAN |
| Immunogen | Synthesized peptide derived from part of the human protein |
| Specificity | CAN6 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Microtubule-stabilizing protein that may be involved in the regulation of microtubule dynamics and cytoskeletal organization. May act as a regulator of RAC1 activity through interaction with ARHGEF2 to control lamellipodial formation and cell mobility. Does not seem to have protease activity as it has lost the active site residues. |
| Protein Name | Calpain-6Calpain-Like Protease X-LinkedCalpamodulinCalpm |
| Database Links | Reactome: R-HSA-1474228 |
| Cellular Localisation | CytoplasmPerinuclear RegionCytoskeletonSpindleDuring Mitose Associated With The Mitotic SpindleAt Telophase Colocalized To The Midbody Spindle |
| Alternative Antibody Names | Anti-Calpain-6 antibodyAnti-Calpain-Like Protease X-Linked antibodyAnti-Calpamodulin antibodyAnti-Calpm antibodyAnti-CAPN6 antibodyAnti-CALPM antibodyAnti-CANPX antibody |
Information sourced from Uniprot.org