| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CAPN10 (1-230) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CAPN10 |
| Gene ID: |
11132 |
| Uniprot ID: |
CAN10_HUMAN |
| Immunogen Region: |
1-230 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human CAPN10 (NP_075571.1). |
| Immunogen Sequence: |
MRAGRGATPARELFRDAAFP AADSSLFCDLSTPLAQFRED ITWRRPQEICATPRLFPDDP REGQVKQGLLGDCWFLCACA ALQKSRHLLDQVIPPGQPSW ADQEYRGSFTCRIWQFGRWV EVTTDDRLPCLAGRLCFSRC QREDVFWLPLLEKVYAKVHG SYEHLWAGQVADALVDLTGG LAERWNLKGVAGSGGQQDRP GRWEHRTCRQLLHLKDQCLI SCCVLSPRAG |
| Tissue Specificity | Detected in primary skeletal muscle cells (at protein level). Ubiquitous. |
| Function | Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. May play a role in insulin-stimulated glucose uptake. |
| Protein Name | Calpain-10Calcium-Activated Neutral Proteinase 10Canp 10 |
| Database Links | Reactome: R-HSA-1474228 |
| Alternative Antibody Names | Anti-Calpain-10 antibodyAnti-Calcium-Activated Neutral Proteinase 10 antibodyAnti-Canp 10 antibodyAnti-CAPN10 antibodyAnti-KIAA1845 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
