• Western blot analysis of lysates from wild type (WT) and MPP2 knockout (KO) 293T cells, using [KO Validated] MPP2 Rabbit polyclonal antibody (STJ11100785) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 10S.

Anti-MPP2 antibody (1-230) (STJ11100785)

SKU:
STJ11100785

£129.50 - £639.50
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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-MPP2 (1-230) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: MPP2
Gene ID: 4355
Uniprot ID: MPP2_HUMAN
Immunogen Region: 1-230
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-230 of human MPP2 (NP_005365.3).
Immunogen Sequence: MPVAATNSETAMQQVLDNLG SLPSATGAAELDLIFLRGIM ESPIVRSLAKAHERLEETKL EAVRDNNLELVQEILRDLAH VAEQSSTAAELAHILQEPHF QSLLETHDSVASKTYETPPP SPGLDPTFSNQPVPPDAVRM VGIRKTAGEHLGVTFRVEGG ELVIARILHGGMVAQQGLLH VGDIIKEVNGQPVGSDPRAL QELLRNASGSVILKILPSYQ EPHLPRQVFV
Post Translational Modifications Phosphorylated by SRC.
Function Postsynaptic MAGUK scaffold protein that links CADM1 cell adhesion molecules to core components of the postsynaptic density. In CA1 pyramidal neurons, required for synaptic KCNN2-containing channel function and long-term potentiation expression. Seems to negatively regulate SRC function in epithelial cells.
Protein Name Maguk P55 Subfamily Member 2
Discs Large Homolog 2
Protein Mpp2
Cellular Localisation Cytoplasm
Cytoskeleton
Membrane
Cell Projection
Dendrite
Postsynaptic Density
Prominently Expressed In The Postsynaptic Densities Of Dendritic Spines
Is Also Detected In Dendritic Shafts
Alternative Antibody Names Anti-Maguk P55 Subfamily Member 2 antibody
Anti-Discs Large Homolog 2 antibody
Anti-Protein Mpp2 antibody
Anti-MPP2 antibody
Anti-DLG2 antibody

Information sourced from Uniprot.org

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