Anti-CapG antibody (1-348aa) [AT1D10] (STJA0041794)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG2bk
ImmunogenRecombinant human CAPG (1-348aa) purified from E. coli
General Information
| Short Description | Mouse monoclonal anti-CapG (1-348aa) for use in ELISA, WB, ICC and IF in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/WB/ICC/IF |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | AT1D10 |
| Isotype | IgG2bk |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | By protein-A affinity chromatography |
| Formulation | Liquid in phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CAPG |
| Gene ID | 822 |
| Uniprot ID | CAPG_HUMAN |
| Accession Number | AAH00728 |
| Immunogen | Recombinant human CAPG (1-348aa) purified from E. coli |
| Immunogen Region | 1-348aa |
Additional Info
| Tissue Specificity | Macrophages and macrophage-like cells. |
| Post Translational Modifications | The N-terminus is blocked. |
| Function | Calcium-sensitive protein which reversibly blocks the barbed ends of actin filaments but does not sever preformed actin filaments. May play an important role in macrophage function. May play a role in regulating cytoplasmic and/or nuclear structures through potential interactions with actin. May bind DNA. |
| Protein Name | Macrophage-Capping ProteinActin Regulatory Protein Cap-G |
| Database Links | |
| Cellular Localisation | NucleusCytoplasmMelanosomeCell ProjectionLamellipodiumRuffleIn MacrophagesMay Be Predominantly CytoplasmicNuclear Localization Was Observed In FibroblastsPresent At The Membrane-Cytoplasm InterfaceIn Activated MacrophagesConcentrated In The Ruffles Of The Leading Lamellipodia |
| Alternative Antibody Names | Anti-Macrophage-Capping Protein antibodyAnti-Actin Regulatory Protein Cap-G antibodyAnti-CAPG antibodyAnti-AFCP antibodyAnti-MCP antibody |
Information sourced from Uniprot.org