| Host: |
Goat |
| Applications: |
Pep-ELISA/WB |
| Reactivity: |
Human |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Goat polyclonal antibody anti-Cannabinoid Receptor 2 (C-Term) is suitable for use in ELISA and Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Purification: |
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Concentration: |
0.5 mg/mL |
| Dilution Range: |
WB-1.5-4.5µg/mlELISA-antibody detection limit dilution 1:32000. |
| Storage Instruction: |
Store at-20°C on receipt and minimise freeze-thaw cycles. |
| Gene Symbol: |
CNR2 |
| Gene ID: |
1269 |
| Uniprot ID: |
CNR2_HUMAN |
| Immunogen Region: |
C-Term |
| Accession Number: |
NP_001832.1 |
| Immunogen Sequence: |
TETEADGKITPWPD |
| Post Translational Modifications | Constitutively phosphorylated on Ser-352.phosphorylation increases cell internalization and desensitizes the receptor. |
| Function | Heterotrimeric G protein-coupled receptor for endocannabinoid 2-arachidonoylglycerol mediating inhibition of adenylate cyclase. May function in inflammatory response, nociceptive transmission and bone homeostasis. |
| Protein Name | Cannabinoid Receptor 2Cb-2Cb2Hcb2Cx5 |
| Database Links | Reactome: R-HSA-373076Reactome: R-HSA-418594 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinCell ProjectionDendritePerikaryonLocalizes To Apical Dendrite Of Pyramidal Neurons |
| Alternative Antibody Names | Anti-Cannabinoid Receptor 2 antibodyAnti-Cb-2 antibodyAnti-Cb2 antibodyAnti-Hcb2 antibodyAnti-Cx5 antibodyAnti-CNR2 antibodyAnti-CB2A antibodyAnti-CB2B antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
