Anti-CAMK1D antibody (C-Term) (STJ71852)
SPECIFICATIONS
ClonalityPolyclonal
HostGoat
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Goat polyclonal antibody anti-CAMK1D (C-Term) is suitable for use in ELISA and Western Blot research applications. |
| Applications | Pep-ELISA/WB |
| Host | Goat |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.5 mg/mL |
| Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
| Dilution Range | Peptide ELISA: antibody detection limit dilution 1:4000.WB: Approx. 40kDa band observed in Human Liver lysates (calculated MW of 40.2kDa according to NP_065130.1). Recommended concentration: 1-3ยตg/ml. |
| Formulation | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA |
| Storage Instruction | Store at-20ยฐC on receipt and minimise freeze-thaw cycles. |
Target Information
| Gene Symbol | CAMK1D |
| Gene ID | 57118 |
| Uniprot ID | KCC1D_HUMAN |
| Accession Number | NP_065130.1 |
| Immunogen Region | C-Term |
| Immunogen Sequence | ASQKDCAYVAKPES |
| Specificity | This antibody is expected to recognize reported isoform 1 (NP_065130.1). |
Additional Info
| Function | Calcium/calmodulin-dependent protein kinase that operates in the calcium-triggered CaMKK-CaMK1 signaling cascade and, upon calcium influx, activates CREB-dependent gene transcription, regulates calcium-mediated granulocyte function and respiratory burst and promotes basal dendritic growth of hippocampal neurons. In neutrophil cells, required for cytokine-induced proliferative responses and activation of the respiratory burst. Activates the transcription factor CREB1 in hippocampal neuron nuclei. May play a role in apoptosis of erythroleukemia cells. In vitro, phosphorylates transcription factor CREM isoform Beta. |
| Protein Name | Calcium/Calmodulin-Dependent Protein Kinase Type 1dCam Kinase I DeltaCam Kinase IdCam-Ki DeltaCamki DeltaCamkidCamki-Like Protein KinaseCklik |
| Cellular Localisation | CytoplasmNucleusPredominantly CytoplasmicNuclear Localization Increases Upon Activation By Kcl Treatment In Hippocampal Neurons |
| Alternative Antibody Names | Anti-Calcium/Calmodulin-Dependent Protein Kinase Type 1d antibodyAnti-Cam Kinase I Delta antibodyAnti-Cam Kinase Id antibodyAnti-Cam-Ki Delta antibodyAnti-Camki Delta antibodyAnti-Camkid antibodyAnti-Camki-Like Protein Kinase antibodyAnti-Cklik antibodyAnti-CAMK1D antibodyAnti-CAMKID antibody |
Information sourced from Uniprot.org