| Host: |
Rabbit |
| Applications: |
WB/IF |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-CAMK1D (1-180) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:500-1:2000IF/ICC 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CAMK1D |
| Gene ID: |
57118 |
| Uniprot ID: |
KCC1D_HUMAN |
| Immunogen Region: |
1-180 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human CAMK1D (NP_705718.1). |
| Immunogen Sequence: |
MARENGESSSSWKKQAEDIK KIFEFKETLGTGAFSEVVLA EEKATGKLFAVKCIPKKALK GKESSIENEIAVLRKIKHEN IVALEDIYESPNHLYLVMQL VSGGELFDRIVEKGFYTEKD ASTLIRQVLDAVYYLHRMGI VHRDLKPENLLYYSQDEESK IMISDFGLSKMEGKGDVMST |
| Tissue Specificity | Widely expressed. Highly and mostly expressed in polymorphonuclear leukocytes (neutrophilic and eosinophilic granulocytes) while little or no expression is observed in monocytes and lymphocytes. |
| Function | Calcium/calmodulin-dependent protein kinase that operates in the calcium-triggered CaMKK-CaMK1 signaling cascade and, upon calcium influx, activates CREB-dependent gene transcription, regulates calcium-mediated granulocyte function and respiratory burst and promotes basal dendritic growth of hippocampal neurons. In neutrophil cells, required for cytokine-induced proliferative responses and activation of the respiratory burst. Activates the transcription factor CREB1 in hippocampal neuron nuclei. May play a role in apoptosis of erythroleukemia cells. In vitro, phosphorylates transcription factor CREM isoform Beta. |
| Protein Name | Calcium/Calmodulin-Dependent Protein Kinase Type 1dCam Kinase I DeltaCam Kinase IdCam-Ki DeltaCamki DeltaCamkidCamki-Like Protein KinaseCklik |
| Cellular Localisation | CytoplasmNucleusPredominantly CytoplasmicNuclear Localization Increases Upon Activation By Kcl Treatment In Hippocampal Neurons |
| Alternative Antibody Names | Anti-Calcium/Calmodulin-Dependent Protein Kinase Type 1d antibodyAnti-Cam Kinase I Delta antibodyAnti-Cam Kinase Id antibodyAnti-Cam-Ki Delta antibodyAnti-Camki Delta antibodyAnti-Camkid antibodyAnti-Camki-Like Protein Kinase antibodyAnti-Cklik antibodyAnti-CAMK1D antibodyAnti-CAMKID antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
