Anti-Calretinin antibody [MX027] (STJ16101841)

SKU:
STJ16101841-1

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Host: Mouse
Applications: IHC-P
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Mouse monoclonal antibody anti-Calretinin is suitable for use in Immunohistochemistry research applications.
Clonality: Monoclonal
Clone ID: MX027
Conjugation: Unconjugated
Isotype: IgG
Formulation: Tissue culture supernatant containing 15mM sodium azide
Purification: Concentrate
Dilution Range: IHC-P 1:400-1:800
Storage Instruction: Store at 2-8°C upon receipt.
Background Calretinin is a 29 kDa calcium-binding protein, member of the family of so-called EF-hand proteins, to which also the S-100 proteins belong. Calretinin is abundantly expressed in neurons. Outside the nervous system, calretinin is found in mesothelial cells, steroid producing cells (adrenal cortical cells, testicular Leydig cells, ovarian theca internal cells) , testicular Sertoli cells, rete testis, ovarian surface epithelium, some neuroendocrine cells, breast glands, eccrine sweat glands, hair follicular cells, thymic epithelial cells, endometrial stromal cells and fat cells. In calretinin positive cells, the protein is generally found in both cytoplasm and nuclei. Pre-treatment: Heat induced epitope retrieval in 10 mM citrate buffer pH6.0 for 20 minutes is required for IHC staining on formalin-fixed, paraffin embedded tissue sections. Note: Dilution of the antibody in 10% normal goat serum followed by a goat anti-mouse secondary antibody-based detection is recommended. Control tissue Brain tissue and mesothelioma. Staining cytoplasmic, nuclear.

Information sourced from Uniprot.org

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