Anti-Calmegin antibody (180-350) [S7MR] (STJ11103067)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit monoclonal Calmegin (180-350) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | S7MR |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 0.05% BSA, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CLGN |
| Gene ID | 1047 |
| Uniprot ID | CLGN_HUMAN |
| Immunogen Region | 180-350 |
| Immunogen Sequence | FGPDKCGEDYKLHFIFRHKH PKTGVFEEKHAKPPDVDLKK FFTDRKTHLYTLVMNPDDTF EVLVDQTVVNKGSLLEDVVP PIKPPKEIEDPNDKKPEEWD ERAKIPDPSAVKPEDWDESE PAQIEDSSVVKPAGWLDDEP KFIPDPNAEKPDDWNEDTDG EWEAPQILNPA |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 180-350 of human Calmegin (O14967). |
Additional Info
| Tissue Specificity | Detected in testis (at protein level). Detected in testis. |
| Function | Functions during spermatogenesis as a chaperone for a range of client proteins that are important for sperm adhesion onto the egg zona pellucida and for subsequent penetration of the zona pellucida. Required for normal sperm migration from the uterus into the oviduct. Required for normal male fertility. Binds calcium ions. |
| Protein Name | Calmegin |
| Database Links | |
| Cellular Localisation | Endoplasmic Reticulum MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Calmegin antibodyAnti-CLGN antibody |
Information sourced from Uniprot.org