Anti-CALHM2 antibody (STJA0008860)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human CALHM2
General Information
| Short Description | Rabbit polyclonal anti-Calcium homeostasis modulator protein 2 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CALHM2 |
| Gene ID | 51063 |
| Uniprot ID | CAHM2_HUMAN |
| Immunogen | Synthesized peptide derived from human CALHM2 |
| Specificity | This antibody detects endogenous levels of CALHM2 at Human, Mouse, Rat |
Additional Info
| Function | Pore-forming subunit of Ca(2+) homeostasis modulator channels. Mediates ATP release from astrocytes and ATP-induced Ca(2+) influx in microglia thus regulating neuronal ATP and Ca(2+) homeostasis, synaptic transmission and neuroinflammatory response. May form intercellular gap junctions. The gating mechanism remains unknown. |
| Protein Name | Calcium Homeostasis Modulator Protein 2Protein Fam26b |
| Database Links | |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Calcium Homeostasis Modulator Protein 2 antibodyAnti-Protein Fam26b antibodyAnti-CALHM2 antibodyAnti-FAM26B antibody |
Information sourced from Uniprot.org