• Western blot analysis of extracts of various cell lines, using CALCRL antibody (STJ111275) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% non-fat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 15s.
  • Western blot analysis of extracts of various cell lines, using CALCRL antibody (STJ111275) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 15s.

Anti-CALCRL antibody (430-461) (STJ111275)

SKU:
STJ111275

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Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-CALCRL (430-461) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CALCRL
Gene ID: 10203
Uniprot ID: CALRL_HUMAN
Immunogen Region: 430-461
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 430-461 of human CALCRL (NP_005786.1).
Immunogen Sequence: PGYSHDCPSEHLNGKS
Tissue Specificity Predominantly expressed in the lung and heart.
Function Receptor for calcitonin-gene-related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP3. Receptor for adrenomedullin together with RAMP2. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
Protein Name Calcitonin Gene-Related Peptide Type 1 Receptor
Cgrp Type 1 Receptor
Calcitonin Receptor-Like Receptor
Database Links Reactome: R-HSA-418555
Reactome: R-HSA-419812
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Calcitonin Gene-Related Peptide Type 1 Receptor antibody
Anti-Cgrp Type 1 Receptor antibody
Anti-Calcitonin Receptor-Like Receptor antibody
Anti-CALCRL antibody
Anti-CGRPR antibody

Information sourced from Uniprot.org

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