Anti-CALCB antibody (1-127) (STJ110404)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal CALCB (1-127) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.09% Sodium Azide, 50% Glycerol, pH7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CALCB |
| Gene ID | 797 |
| Uniprot ID | CALCB_HUMAN |
| Immunogen Region | 1-127 |
| Immunogen Sequence | MGFRKFSPFLALSILVLYQA GSLQAAPFRSALESSPDPAT LSKEDARLLLAALVQDYVQM KASELKQEQETQGSSSAAQK RACNTATCVTHRLAGLLSRS GGMVKSNFVPTNVGSKAFGR RRRDLQA |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-127 of human CALCB (NP_000719.1). |
Additional Info
| Tissue Specificity | Expressed in spinal cord, pituitary and thalamus. |
| Function | CALCB/CGRP2 is a peptide hormone that induces vasodilation mediated by the CALCRL-RAMP1 receptor complex. Dilates a variety of vessels including the coronary, cerebral and systemic vasculature. Its abundance in the CNS also points toward a neurotransmitter or neuromodulator role. |
| Protein Name | Calcitonin Gene-Related Peptide 2Cgrp2Beta-Type CgrpBeta-CgrpCalcitonin Gene-Related Peptide IiCgrp-Ii |
| Database Links | Reactome: R-HSA-418555Reactome: R-HSA-419812 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Calcitonin Gene-Related Peptide 2 antibodyAnti-Cgrp2 antibodyAnti-Beta-Type Cgrp antibodyAnti-Beta-Cgrp antibodyAnti-Calcitonin Gene-Related Peptide Ii antibodyAnti-Cgrp-Ii antibodyAnti-CALCB antibodyAnti-CALC2 antibody |
Information sourced from Uniprot.org