Anti-CADPS2 antibody (STJ190634)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from part of the human protein
General Information
| Short Description | Rabbit polyclonal anti-Calcium-dependent secretion activator 2 for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CADPS2 |
| Gene ID | 93664 |
| Uniprot ID | CAPS2_HUMAN |
| Immunogen | Synthesized peptide derived from part of the human protein |
| Specificity | CAPS2 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Calcium-binding protein involved in exocytosis of vesicles filled with neurotransmitters and neuropeptides. Probably acts upstream of fusion in the biogenesis or maintenance of mature secretory vesicles. Regulates neurotrophin release from granule cells leading to regulate cell differentiation and survival during cerebellar development. May specifically mediate the Ca(2+)-dependent exocytosis of large dense-core vesicles (DCVs) and other dense-core vesicles. |
| Protein Name | Calcium-Dependent Secretion Activator 2Calcium-Dependent Activator Protein For Secretion 2Caps-2 |
| Database Links | |
| Cellular Localisation | Cytoplasmic Vesicle MembranePeripheral Membrane ProteinCytoplasmic SideSynapseCell ProjectionCiliumCytoplasmCytoskeletonCilium Basal BodyMicrotubule Organizing CenterCentrosomeMembrane-Associated To VesiclesStrongly Enriched In Synaptic FraCtionsProbably Localizes To Different Vesicles Compared To CadpsEnriched On Vesicular Structures In The Parallel Fiber Terminal Of Granule Cells That Are Distinct From Synaptic Vesicles |
| Alternative Antibody Names | Anti-Calcium-Dependent Secretion Activator 2 antibodyAnti-Calcium-Dependent Activator Protein For Secretion 2 antibodyAnti-Caps-2 antibodyAnti-CADPS2 antibodyAnti-CAPS2 antibodyAnti-KIAA1591 antibody |
Information sourced from Uniprot.org