Anti-CACNG8 antibody (140-220 aa) (STJ191628)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 140-220
General Information
| Short Description | Rabbit polyclonal anti-Voltage-dependent calcium channel gamma-8 subunit (140-220 aa) for use in WB and ELISA in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CACNG8 |
| Gene ID | 59283 |
| Uniprot ID | CCG8_HUMAN |
| Immunogen | Synthesized peptide derived from the human protein at the amino acid range 140-220 |
| Immunogen Region | 140-220 aa |
| Specificity | CCG8 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Post Translational Modifications | Palmitoylated. Probably palmitoylated by ZDHHC3 and ZDHHC7. |
| Function | Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit. Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. |
| Protein Name | Voltage-Dependent Calcium Channel Gamma-8 SubunitNeuronal Voltage-Gated Calcium Channel Gamma-8 SubunitTransmembrane Ampar Regulatory Protein Gamma-8Tarp Gamma-8 |
| Database Links | Reactome: R-HSA-399719Reactome: R-HSA-5576892Reactome: R-HSA-5576893Reactome: R-HSA-5682910 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinPostsynaptic Density Membrane |
| Alternative Antibody Names | Anti-Voltage-Dependent Calcium Channel Gamma-8 Subunit antibodyAnti-Neuronal Voltage-Gated Calcium Channel Gamma-8 Subunit antibodyAnti-Transmembrane Ampar Regulatory Protein Gamma-8 antibodyAnti-Tarp Gamma-8 antibodyAnti-CACNG8 antibodyAnti-CACNG6 antibody |
Information sourced from Uniprot.org