| Short Description : | Rabbit polyclonal anti-CACNG7 (N-Term) for use in IHC and WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | IHC/WB |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Purification: | IgG purified |
| Dilution Range: | IHC, WB. A concentration of 10-50 µg/ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications. |
| Formulation: | Lyophilised |
| Storage Instruction: | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
| Gene Symbol: | CACNG7 |
| Gene ID: | 59284 |
| Uniprot ID: | CCG7_HUMAN |
| Immunogen: | A synthetic peptide from the n-terminal region of human CACNG7 conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in mouse and rat. |
| Immunogen Region: | N-Term |
| Specificity: | Specific for CACNG7. |
| Function | Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit. Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Displays subunit-specific AMPA receptor regulation. Shows specificity only for GRIA1 and GRIA2. |
| Protein Name | Voltage-Dependent Calcium Channel Gamma-7 SubunitNeuronal Voltage-Gated Calcium Channel Gamma-7 SubunitTransmembrane Ampar Regulatory Protein Gamma-7Tarp Gamma-7 |
| Database Links | Reactome: R-HSA-5576892Reactome: R-HSA-5576893Reactome: R-HSA-9856532 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Voltage-Dependent Calcium Channel Gamma-7 Subunit antibodyAnti-Neuronal Voltage-Gated Calcium Channel Gamma-7 Subunit antibodyAnti-Transmembrane Ampar Regulatory Protein Gamma-7 antibodyAnti-Tarp Gamma-7 antibodyAnti-CACNG7 antibody |
Information sourced from Uniprot.org
