| Host: |
Rabbit |
| Applications: |
WB/IHC/IF |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Voltage-dependent calcium channel gamma-2 subunit (58-108 aa) is suitable for use in Western Blot, Immunohistochemistry and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS pH7.4, 0.5% BSA, 0.02% Sodium Azide and 50% Glycerol. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range: |
WB 1:1000-2000IHC 1:200-500IF 1:50-200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
CACNG2 |
| Gene ID: |
10369 |
| Uniprot ID: |
CCG2_HUMAN |
| Immunogen Region: |
58-108 aa |
| Specificity: |
The antibody detects endogenous CACNG2 protein. |
| Immunogen: |
Synthetic peptide derived from CACNG2 at the amino acid range 58-108 |
| Post Translational Modifications | Phosphorylation of Thr-321 impairs interaction with DLG1 and DLG4. |
| Function | Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state. |
| Protein Name | Voltage-Dependent Calcium Channel Gamma-2 SubunitNeuronal Voltage-Gated Calcium Channel Gamma-2 SubunitTransmembrane Ampar Regulatory Protein Gamma-2Tarp Gamma-2 |
| Database Links | Reactome: R-HSA-112308Reactome: R-HSA-399719Reactome: R-HSA-5682910 |
| Cellular Localisation | MembraneMulti-Pass Membrane ProteinSynapseSynaptosome |
| Alternative Antibody Names | Anti-Voltage-Dependent Calcium Channel Gamma-2 Subunit antibodyAnti-Neuronal Voltage-Gated Calcium Channel Gamma-2 Subunit antibodyAnti-Transmembrane Ampar Regulatory Protein Gamma-2 antibodyAnti-Tarp Gamma-2 antibodyAnti-CACNG2 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
