• Western blot analysis of various lysates using CACNB3 Rabbit polyclonal antibody (STJ116910) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 90s.

Anti-CACNB3 antibody (355-484) (STJ116910)

SKU:
STJ116910

£169.50 - £449.50
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Host: Rabbit
Applications: WB
Reactivity: Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-CACNB3 (355-484) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CACNB3
Gene ID: 784
Uniprot ID: CACB3_HUMAN
Immunogen Region: 355-484
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 355-484 of human CACNB3 (NP_000716.2).
Immunogen Sequence: VYWRATHHPAPGPGLLGPPS AIPGLQNQQLLGERGEEHSP LERDSLMPSDEASESSRQAW TGSSQRSSRHLEEDYADAYQ DLYQPHRQHTSGLPSANGHD PQDRLLAQDSEHNHSDRNWQ RNRPWPKDSY
Tissue Specificity Expressed mostly in brain, colon and ovary.
Function Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents. Increases CACNA1B peak calcium current and shifts the voltage dependencies of channel activation and inactivation. Increases CACNA1C peak calcium current and shifts the voltage dependencies of channel activation and inactivation.
Protein Name Voltage-Dependent L-Type Calcium Channel Subunit Beta-3
Cab3
Calcium Channel Voltage-Dependent Subunit Beta 3
Database Links Reactome: R-HSA-112308
Reactome: R-HSA-400042
Reactome: R-HSA-419037
Reactome: R-HSA-422356
Cellular Localisation Cytoplasm
Alternative Antibody Names Anti-Voltage-Dependent L-Type Calcium Channel Subunit Beta-3 antibody
Anti-Cab3 antibody
Anti-Calcium Channel Voltage-Dependent Subunit Beta 3 antibody
Anti-CACNB3 antibody
Anti-CACNLB3 antibody

Information sourced from Uniprot.org

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