Anti-CACNB3 antibody (355-484) (STJ116910)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal CACNB3 (355-484) antibody for use in WB and ELISA in mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CACNB3 |
| Gene ID | 784 |
| Uniprot ID | CACB3_HUMAN |
| Immunogen Region | 355-484 |
| Immunogen Sequence | VYWRATHHPAPGPGLLGPPS AIPGLQNQQLLGERGEEHSP LERDSLMPSDEASESSRQAW TGSSQRSSRHLEEDYADAYQ DLYQPHRQHTSGLPSANGHD PQDRLLAQDSEHNHSDRNWQ RNRPWPKDSY |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 355-484 of human CACNB3 (NP_000716.2). |
Additional Info
| Tissue Specificity | Expressed mostly in brain, colon and ovary. |
| Function | Regulatory subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents. Increases CACNA1B peak calcium current and shifts the voltage dependencies of channel activation and inactivation. Increases CACNA1C peak calcium current and shifts the voltage dependencies of channel activation and inactivation. |
| Protein Name | Voltage-Dependent L-Type Calcium Channel Subunit Beta-3Cab3Calcium Channel Voltage-Dependent Subunit Beta 3 |
| Database Links | Reactome: R-HSA-112308Reactome: R-HSA-400042Reactome: R-HSA-419037Reactome: R-HSA-422356Reactome: R-HSA-9856532 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Voltage-Dependent L-Type Calcium Channel Subunit Beta-3 antibodyAnti-Cab3 antibodyAnti-Calcium Channel Voltage-Dependent Subunit Beta 3 antibodyAnti-CACNB3 antibodyAnti-CACNLB3 antibody |
Information sourced from Uniprot.org