Anti-CACNB1 antibody (N-Term) (STJ13100826)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from the n-terminal region of mouse CACNB1 (CAB1) conjugated to an immunogenic carrier protein was used as the antigen. The peptide shares 98% identity with rat and human sequences.
General Information
| Short Description | Rabbit polyclonal anti-CACNB1 (N-Term) for use in IHC and WB in Mouse, Rat and Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Mouse/Rat/Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB. A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | Cacnb1 |
| Gene ID | 12295 |
| Uniprot ID | CACB1_MOUSE |
| Immunogen | A synthetic peptide from the n-terminal region of mouse CACNB1 (CAB1) conjugated to an immunogenic carrier protein was used as the antigen. The peptide shares 98% identity with rat and human sequences. |
| Immunogen Region | N-Term |
| Specificity | Specific for CACNB1. |
Additional Info
| Function | Regulatory subunit of L-type calcium channels. Regulates the activity of L-type calcium channels that contain CACNA1A as pore-forming subunit. Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit and increases the presence of the channel complex at the cell membrane. Required for functional expression L-type calcium channels that contain CACNA1D as pore-forming subunit. Regulates the activity of L-type calcium channels that contain CACNA1B as pore-forming subunit. |
| Protein Name | Voltage-Dependent L-Type Calcium Channel Subunit Beta-1Cab1Calcium Channel Voltage-Dependent Subunit Beta 1 |
| Database Links | Reactome: R-MMU-112308Reactome: -MMU-5576892Reactome: -MMU-5576893 |
| Cellular Localisation | Cell MembraneSarcolemmaPeripheral Membrane ProteinCytoplasmic Side |
| Alternative Antibody Names | Anti-Voltage-Dependent L-Type Calcium Channel Subunit Beta-1 antibodyAnti-Cab1 antibodyAnti-Calcium Channel Voltage-Dependent Subunit Beta 1 antibodyAnti-Cacnb1 antibodyAnti-Cacnlb1 antibody |
Information sourced from Uniprot.org