Host: |
Rabbit |
Applications: |
IHC/WB |
Reactivity: |
Human/Mouse/Rat |
Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Short Description: |
Rabbit polyclonal antibody anti-CACNA2D1 (600-650 aa) is suitable for use in Immunohistochemistry and Western Blot research applications. |
Clonality: |
Polyclonal |
Conjugation: |
Unconjugated |
Isotype: |
IgG |
Formulation: |
Lyophilised |
Purification: |
IgG purified |
Dilution Range: |
IHC, WB. A dilution of 1: 1000 to 1: 3000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
Storage Instruction: |
Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Gene Symbol: |
CACNA2D1 |
Gene ID: |
781 |
Uniprot ID: |
CA2D1_HUMAN |
Immunogen Region: |
600-650 aa |
Specificity: |
Specific for CACNA2D1. |
Immunogen: |
A synthetic peptide from aa region 600-650 of human CACNA2D1 conjugated to blur carrier protein was used as the antigen. The peptide is homologous in rat and mouse. |
Post Translational Modifications | Proteolytically processed into subunits alpha-2-1 and delta-1 that are disulfide-linked. |
Function | The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel. Plays an important role in excitation-contraction coupling. |
Protein Name | Voltage-Dependent Calcium Channel Subunit Alpha-2/Delta-1Voltage-Gated Calcium Channel Subunit Alpha-2/Delta-1 Cleaved Into - Voltage-Dependent Calcium Channel Subunit Alpha-2-1 - Voltage-Dependent Calcium Channel Subunit Delta-1 |
Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinCell Membrane |
Alternative Antibody Names | Anti-Voltage-Dependent Calcium Channel Subunit Alpha-2/Delta-1 antibodyAnti-Voltage-Gated Calcium Channel Subunit Alpha-2/Delta-1 Cleaved Into - Voltage-Dependent Calcium Channel Subunit Alpha-2-1 - Voltage-Dependent Calcium Channel Subunit Delta-1 antibodyAnti-CACNA2D1 antibodyAnti-CACNL2A antibodyAnti-CCHL2A antibodyAnti-MHS3 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance