Anti-CACNA2D1 antibody (600-650 aa) (STJ13100110)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from aa region 600-650 of human CACNA2D1 conjugated to blur carrier protein was used as the antigen. The peptide is homologous in rat and mouse.
General Information
| Short Description | Rabbit polyclonal anti-CACNA2D1 (600-650 aa) for use in IHC and WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB. A dilution of 1: 1000 to 1: 3000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | CACNA2D1 |
| Gene ID | 781 |
| Uniprot ID | CA2D1_HUMAN |
| Immunogen | A synthetic peptide from aa region 600-650 of human CACNA2D1 conjugated to blur carrier protein was used as the antigen. The peptide is homologous in rat and mouse. |
| Immunogen Region | 600-650 aa |
| Specificity | Specific for CACNA2D1. |
Additional Info
| Post Translational Modifications | Proteolytically processed into subunits alpha-2-1 and delta-1 that are disulfide-linked. |
| Function | The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel. Plays an important role in excitation-contraction coupling. |
| Protein Name | Voltage-Dependent Calcium Channel Subunit Alpha-2/Delta-1Voltage-Gated Calcium Channel Subunit Alpha-2/Delta-1 Cleaved Into - Voltage-Dependent Calcium Channel Subunit Alpha-2-1 - Voltage-Dependent Calcium Channel Subunit Delta-1 |
| Database Links | Reactome: R-HSA-9856532 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinCell Membrane |
| Alternative Antibody Names | Anti-Voltage-Dependent Calcium Channel Subunit Alpha-2/Delta-1 antibodyAnti-Voltage-Gated Calcium Channel Subunit Alpha-2/Delta-1 Cleaved Into - Voltage-Dependent Calcium Channel Subunit Alpha-2-1 - Voltage-Dependent Calcium Channel Subunit Delta-1 antibodyAnti-CACNA2D1 antibodyAnti-CACNL2A antibodyAnti-CCHL2A antibodyAnti-MHS3 antibody |
Information sourced from Uniprot.org