Anti-CACNA1D antibody (1060-1140 aa) (STJ197416)

SKU:
STJ197416
£49.00 - £261.00
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Short Description :Rabbit polyclonal anti-Voltage-dependent L-type calcium channel subunit alpha-1D (1060-1140 aa) for use in IHC and IF in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications:IHC/IF
Host:Rabbit
Reactivity:Human/Rat/Mouse
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Polyclonal
Isotype:IgG
Conjugation:Unconjugated
Concentration:1 mg/mL
Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Dilution Range:IHC 1:100-200
IF 1:50-200
Formulation:Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Storage Instruction:Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol:CACNA1D
Gene ID:776
Uniprot ID:CAC1D_HUMAN
Immunogen:Synthetic peptide derived from Cav1.3 at the amino acid range 1060-1140
Immunogen Region:1060-1140 aa
Specificity:Cav1.3 protein (A202) detects endogenous levels of Cav1.3
Function Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1D gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, and by benzothiazepines. Isoform Neuronal-type: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1D gives rise to L-type calcium currents. Isoform 3: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1D gives rise to L-type calcium currents. Isoform 4: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1D gives rise to L-type calcium currents.
Protein Name Voltage-Dependent L-Type Calcium Channel Subunit Alpha-1d
Calcium Channel - L Type - Alpha-1 Polypeptide - Isoform 2
Voltage-Gated Calcium Channel Subunit Alpha Cav1.3
Database Links Reactome: R-HSA-400042
Reactome: R-HSA-419037
Reactome: R-HSA-422356
Reactome: R-HSA-9662360
Cellular Localisation Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Voltage-Dependent L-Type Calcium Channel Subunit Alpha-1d antibody
Anti-Calcium Channel - L Type - Alpha-1 Polypeptide - Isoform 2 antibody
Anti-Voltage-Gated Calcium Channel Subunit Alpha Cav1.3 antibody
Anti-CACNA1D antibody
Anti-CACH3 antibody
Anti-CACN4 antibody
Anti-CACNL1A2 antibody
Anti-CCHL1A2 antibody

Information sourced from Uniprot.org