Anti-CACNA1A antibody (STJ13100948)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from mouse CACNA1A conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat and human.
General Information
| Short Description | Rabbit polyclonal anti-CACNA1A for use in IHC and WB in Mouse, Human and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Mouse/Human/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB. A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | Cacna1a |
| Gene ID | 12286 |
| Uniprot ID | CAC1A_MOUSE |
| Immunogen | A synthetic peptide from mouse CACNA1A conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat and human. |
| Specificity | Specific for CACNA1A. |
Additional Info
| Function | Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q-type calcium currents. P/Q-type calcium channels belong to the 'high-voltage activated' (HVA) group and are specifically blocked by the spider omega-agatoxin-IVA (AC P54282). They are however insensitive to dihydropyridines (DHP). |
| Protein Name | Voltage-Dependent P/Q-Type Calcium Channel Subunit Alpha-1aBrain Calcium Channel IBiCalcium Channel - L Type - Alpha-1 Polypeptide Isoform 4Voltage-Gated Calcium Channel Subunit Alpha Cav2.1 |
| Database Links | Reactome: R-MMU-112308Reactome: -MMU-422356 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane Protein |
| Alternative Antibody Names | Anti-Voltage-Dependent P/Q-Type Calcium Channel Subunit Alpha-1a antibodyAnti-Brain Calcium Channel I antibodyAnti-Bi antibodyAnti-Calcium Channel - L Type - Alpha-1 Polypeptide Isoform 4 antibodyAnti-Voltage-Gated Calcium Channel Subunit Alpha Cav2.1 antibodyAnti-Cacna1a antibodyAnti-Caca1a antibodyAnti-Cach4 antibodyAnti-Cacn3 antibodyAnti-Cacnl1a4 antibodyAnti-Ccha1a antibody |
Information sourced from Uniprot.org