Immunohistochemical analysis of paraffin-embedded human liver cancer. 1, Antibody was diluted at 1:200 (4°C overnight). 2, Tris-EDTA, pH9.0 was used for antigen retrieval. 3, Secondary antibody was diluted at 1:200 (room temperature, 45min).

Anti-CACNA1A antibody (1401-1450 aa) (STJ192574)

SKU:
STJ192574
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Host: Rabbit
Applications: IHC/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description : Rabbit polyclonal antibody anti-Voltage-dependent P/Q-type calcium channel subunit alpha-1A (1401-1450 aa) is suitable for use in Immunohistochemistry and Immunofluorescence research applications.
Clonality : Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: IHC-P 1:50-300
IF 1:50-200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: CACNA1A
Gene ID: 773
Uniprot ID: CAC1A_HUMAN
Immunogen Region: 1401-1450 aa
Specificity: CAC1A Polyclonal Antibody detects endogenous levels of protein.
Immunogen: Synthesized peptide derived from the human protein at the amino acid range 1401-1450
Function Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1A gives rise to P and/or Q-type calcium currents. P/Q-type calcium channels belong to the 'high-voltage activated' (HVA) group and are specifically blocked by the spider omega-agatoxin-IVA (AC P54282). They are however insensitive to dihydropyridines (DHP).
Protein Name Voltage-Dependent P/Q-Type Calcium Channel Subunit Alpha-1a
Brain Calcium Channel I
Bi
Calcium Channel - L Type - Alpha-1 Polypeptide Isoform 4
Voltage-Gated Calcium Channel Subunit Alpha Cav2.1
Database Links Reactome: R-HSA-112308
Reactome: R-HSA-422356
Cellular Localisation Cell Membrane
Multi-Pass Membrane Protein
Alternative Antibody Names Anti-Voltage-Dependent P/Q-Type Calcium Channel Subunit Alpha-1a antibody
Anti-Brain Calcium Channel I antibody
Anti-Bi antibody
Anti-Calcium Channel - L Type - Alpha-1 Polypeptide Isoform 4 antibody
Anti-Voltage-Gated Calcium Channel Subunit Alpha Cav2.1 antibody
Anti-CACNA1A antibody
Anti-CACH4 antibody
Anti-CACN3 antibody
Anti-CACNL1A4 antibody

Information sourced from Uniprot.org

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