Anti-CA9 antibody (52-151) (STJ115637)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal CA9 (52-151) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:50-1:200IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | CA9 |
| Gene ID | 768 |
| Uniprot ID | CAH9_HUMAN |
| Immunogen Region | 52-151 |
| Immunogen Sequence | GSSGEDDPLGEEDLPSEEDS PREEDPPGEEDLPGEEDLPG EEDLPEVKPKSEEEGSLKLE DLPTVEAPGDPQEPQNNAHR DKEGDDQSHWRYGGDPPWPR |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 52-151 of human Carbonic Anhydrase 9 (CA9/G250) (NP_001207.2). |
Additional Info
| Tissue Specificity | Expressed primarily in carcinoma cells lines. Expression is restricted to very few normal tissues and the most abundant expression is found in the epithelial cells of gastric mucosa. |
| Post Translational Modifications | Asn-346 bears high-mannose type glycan structures. |
| Function | Catalyzes the interconversion between carbon dioxide and water and the dissociated ions of carbonic acid (i.e. bicarbonate and hydrogen ions). |
| Protein Name | Carbonic Anhydrase 9Carbonate Dehydratase IxCarbonic Anhydrase IxCa-IxCaixMembrane Antigen MnP54/58nRenal Cell Carcinoma-Associated Antigen G250Rcc-Associated Antigen G250Pmw1 |
| Database Links | Reactome: R-HSA-1234158Reactome: R-HSA-1475029 |
| Cellular Localisation | NucleusNucleolusCell MembraneSingle-Pass Type I Membrane ProteinCell ProjectionMicrovillus MembraneFound On The Surface Microvilli And In The NucleusParticularly In Nucleolus |
| Alternative Antibody Names | Anti-Carbonic Anhydrase 9 antibodyAnti-Carbonate Dehydratase Ix antibodyAnti-Carbonic Anhydrase Ix antibodyAnti-Ca-Ix antibodyAnti-Caix antibodyAnti-Membrane Antigen Mn antibodyAnti-P54/58n antibodyAnti-Renal Cell Carcinoma-Associated Antigen G250 antibodyAnti-Rcc-Associated Antigen G250 antibodyAnti-Pmw1 antibodyAnti-CA9 antibodyAnti-G250 antibodyAnti-MN antibody |
Information sourced from Uniprot.org