Anti-CA19-9 antibody [4701] (STJ400025)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG3
ImmunogenAntibody binds to sialylated Lewis a (sLea) pentasaccharide.
General Information
| Short Description | Mouse monoclonal anti-CA19-9 for use in FIA in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | FIA |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 4701 |
| Isotype | IgG3 |
| Conjugation | Unconjugated |
| Concentration | 5.0 mg/ml (+/-10 %) |
| Formulation | 50 mM citrate, pH 6.0, 0.9 % NaCI, 0.095 % NaN3 as a preservative |
| Storage Instruction | Store at 2–8 °C, and do not freeze. |
Target Information
| Immunogen | Antibody binds to sialylated Lewis a (sLea) pentasaccharide. |
| Specificity | Antibody recognizes carbohydrate antigen 19-9 (CA19-9). Does not recognize cancer antigens CA125 or CA15-3. Does not recognize sialylated Lewis x (sLex) or Lewis y carbohydrate structures. Minor cross-reactivity against sialylated Lewis c (sLec) carb |
Additional Info
| Background | Carbohydrate antigen 19-9 (CA19-9) is a specific carbohydrate epitope called sialylated Lewis-a pentasaccharide, also known as sLea antigen. This epitope is found on several glycoproteins, including Mucin-1. In healthy individuals, the serum concentration of CA19-9 is low, but it increases during gastrointestinal malignancies, including pancreatic cancer, pancreatic or hepatobiliary adenocarcinoma, or colon cancer. |
Information sourced from Uniprot.org